Integrin signalling adaptors: not only figurants in the cancer story
نویسندگان
چکیده
منابع مشابه
Phospholipid signalling: Rho is only ARF the story
Small GTP-binding proteins act as switches that control diverse cellular processes. Those in the ADP-ribosylation factor (ARF) class direct key steps in intracellular protein traffic, whereas those in the Rho family regulate gene transcription as well as changes in cell motility and morphology [1,2]. Several groups have now produced evidence that these regulatory activities of Rho and ARF prote...
متن کاملBiology is only part of the story ...
The origins and development of human cognition constitute one of the most interesting questions to which archaeology can contribute today. In this paper, we do so by presenting an overview of the evolution of artefact technology from the maker's point of view, and linking that development to some hypotheses on the evolution of human cognitive capacity. Our main hypothesis is that these data ind...
متن کاملTranscriptional regulation is only half the story
This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and thendistribute the resultingwork under the sameorsimilar license to thisone. Thework must be attributed back to the original author and commercial use is not permitted without specif...
متن کاملBiological Passports! Only half the story!
1 Michael R. Graham, Llantarnam Research Academy, Newport Road, Llantarnam, Cwmbran, NP44 3AF, UK. 2 Bruce Davies, Health and Exercise Science Department, University of South Wales, CF37 1DL, UK 3 Julien S Baker, Director of Research, Institute of Clinical Exercise and Health Science, Exercise Science Research Laboratory, School of Science, University of the West of Scotland, Hamilton, Lanarksh...
متن کاملSignalling adaptors used by Toll-like receptors: an update.
Research into the five Toll/IL1 receptor (TIR) adaptor proteins involved in innate immunity continues to advance. Here we outline some of the more recent findings. MyD88 has a key role in signalling by the IL1 receptor complex and TLRs. However, a MyD88-independent pathway of IL1beta signalling in neurons has been described which involves the protein kinase Akt, and which has an anti-apoptotic ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2010
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc2967